Bubble Plot from Scientific Research

WikiPathways enrichment results are visualized, with dot size correlating to the gene count for each function and color intensity reflecting p -value significance darker hues indicate higher pathway enrichment (top10 of positive and negative NES, padj < 0.05, padj calculated by GSEApy python package, For the statistical analysis, we used the p value adjustment to control for multiple comparisons. The enrichment scores were evaluated as two-sided, considering both positive and negative deviations from the expected distribution under the null hypothesis).

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