Heatmap of total abundance of differential KEGG pathways at BRITE hierarchy level 3 in each response group. Boxplots indicate the median (middle line), 25th, 75th percentile (box) and 5th and 95th percentile (whiskers). Differences in ( a ) and ( b ) were tested using unpaired two-sided MannWhitney U-test with 95% confidence interval. The asterisk *** P < 0.001, and ns denotes P > 0.05 (detailed P-values are shown in source data). The whiskers in ( c ) represent the clustering of KEGG pathways. Source data are provided as a Source Data file.
