Frequency distribution and comparison of taxa genome size in archaea positively and negatively responding to salinity, of all Euryarchaeota and Thaumarchaeota , and of salt-tolerant archaea found in published literature ( n =1369 for all Thaumarchaeota taxa group; n =5389 for all Euryarchaeota taxa group; n =1603 for survey taxa group; n =44 for neg-arch group; n =47 for pos-arch group). The pie chart in the phylogenetic tree represents the distribution of taxa of adjacent phyla in the four response groups. Boxplots indicate the median (middle line), 25th, 75th percentile (box) and 5 th and 95 th percentile (whiskers). Differences in ( b , c and d ) were tested using unpaired two-sided MannWhitney U- test with 95% confidence interval. The dashed lines in ( c ) and ( d ) denote the median of the dataset. The asterisk *** P <0.001 (detailed P -values are shown in source data). Source data are provided as a Source Data file.