Heatmap from Scientific Research

Hierarchical clustering of RT signals in 50 kb windows across the genome. The Euclidean distance and the ward criterion were used to cluster RT signals of 31 cell lines (including 15 IN-STUDY and 16 ENCODE cell lines). Additional information about the cell lines, including whether the cell line was derived from normal or cancer cells and the presence of different driver gene mutations, are displayed on the top tracks. Names of a subset of cell lines were coloured regarding their involvement in the corresponding cancer type in further analyses. A549 was Repli-sequenced as part of both the ENCODE and our IN-STUDY cohort representing two replicates; A549(E) presents the results using the ENCODE data.

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