Line Plot from Scientific Research

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Effects of clone 19, clone 2, Nivo_mIgG1, Nivo_D265A, and Nivo_Plus on T cell activation in a co-culture NFAT reporter system. Jurkat T cells expressing hPD-1 and a luciferase reporter driven by an NFAT response element (NFATrep) were cultured with TCS cells expressing an anti-CD3 (OKT3) scFv antibody construct. Signaling effects of PD-1 antibodies were measured in four settings: Jurkat PD-1 cells cultured with TCS cells expressing mFcγR2b. The dashed horizontal line in each plot indicates the level of luciferase production by resting Jurkat T cells.
#Line Plot#Error Bars#Illustration#Clone 19#Clone 2#Nivo_mIgG1#Nivo_D265A#Nivo_Plus#T Cell Activation#NFAT Reporter System#Jurkat T Cells#hPD-1#Luciferase#Anti-CD3 Antibodies
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