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Schematic of neuronal activity-dependent recruitment of cAMPPKA signalling in astrocytes, mediated by adenosine and A2B receptors. AC, adenylyl cyclase. In panels d , e , h , traces show averaged (mean s.e.m.) recordings from several individual cells in a representative experiment. In panels c , f , g , i , the numbers in parentheses indicate the number of individual cells or number of separate cultures/slices prepared from the same number of animals. P values were determined by one-way ANOVA followed by Sidak’s or Dunnett’s post-hoc test.

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