Protein Structure from Scientific Research

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The drug-free (apo-Cx36) and drug-bound structures of Cx36, in surface representation, colored according to electrostatic potential (scale bar: 5/+5 kT/e). Drug binding changes pore electrostatics (mefloquine) and/or introduces a steric barrier (quinine, quinidine).
#Protein Structure#Drug-free#Apo-Cx36#Drug-bound Structures#Cx36#Surface Representation#Electrostatic Potential#Mefloquine#Quinine#Quinidine
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