Scatter Plot from Scientific Research

Global changes of gene expression due to inhibition of RNLTR12-int in differentiating OPC as determined by RNA-seq (GEO: GSE237744). Left: volcano plot representing differential expression, up- (red dot) and downregulated (green dot) genes. Right: GO-term overrepresented in differentially expressed genes. p adj: adjusted p value (Benjamini-Hochberg FDR after Wald test). Genes involved in myelination (green bars) are downregulated. n = 4 (control siRNA), 3 (siRNLTR12-int) independent experiments. See alsoFigures S4andS5.

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