Protein Structure from Scientific Research

Molecular interactions between GyrA and LEI-800. LEI-800 is shown as stick representation. The main GyrA residues important for LEI-800 binding are labelled. Key hydrogen bonds (between side-chain and main-chain oxygens of Ser97 and N3 nitrogen of central pyrrolidine ring of LEI-800; main chain nitrogen of Ser172, side-chain nitrogen of Lys42 and sulfonic acid of LEI-800 are shown in gold and distances in Angstrom are indicated.

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