Scatter Plot from Scientific Research

Measured yield (average of three repeats) for the target cross-coupling reaction plotted against experiment batch (eight sequential batches). The highest yield attained after eight batches (optimization steps 07) was 67%. Black points refer to a baseline control experiment conducted for a set of 15 molecules chosen in a way that maximized the structural diversity of the set. The structure of the most active of the 55 molecules evaluated, CNP-127, is also shown.

DOI