Representative RiPP families in the prokaryote-phage interaction network. The BGCs of the representative RiPP families (RF35244, RF7564, RF27583, RF1197) in the interaction network were plotted, and only the core regions were colored. The RiPP precursor of the known family was labeled using the corresponding Pfam domains. The defense systems co-expressed with the neighboring RiPP families (<= 50 kbp upstream/downstream) were plotted and labeled. The RiPP subclasses in the bracket were assigned based on the class-defining PTMs. The bacteria-phage interactions that the corresponding RiPP families may mediate were labeled on the straight right side of the BGCs (except for RF35244, on the right bottom of the BGC)
