The prioritized RiPP-involving phage-host interaction network. For visualization, the prioritized network with WGCNA adjacency larger than 0.125 was selected and shown in the Sankey diagram, and the whole network (WGCNA adjacency > 0) was summarized in Figure S 29. The node column from left to right denoted the prokaryotic phyla (host), RiPP families colored by confidence (at least one member of the RiPP family having neighboring PTMs within ten genes in the vicinity is defined as high confidence, and vice versa; Methods ), functional categories of viral protein families, and phage taxon. The numbers in the brackets represented the flows (interactions) between nodes. For example, Bacteroidota was the source of 11,103 flows, and Caudoviricetes was the target of 4002 flows. The character class in the bracket represented the phage class