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Cell-associated HIV-1 RNA copies in purified CD4+T from study participants receiving panobinostat and pegylated IFN-α2a cells normalized to 1 g of cellular RNA. Seven different viral transcripts were analyzed: readthrough (RT), long LTR, Gag, Pol, Nef, polyA, and Tat/Rev. Empty symbols represent the limit of detection (LOD), defined as the total number of cells assayed without target identification. In (B) and (C), vertical bars reflect the mean with SEM; in (E), vertical bars reflect the geometric mean.*p < 0.05,**p < 0.01, Friedman test followed by Dunn’s multiple comparisons or Wilcoxon matched-pairs signed rank test. See alsoFigure S1.
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