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Inter- and intra-species host specificity of the rumen viruses exemplified with one of the RUG2 samples [46 ], ERR3275126. Each circle represents one microbial genome and is color-coded based on species, while each square represents one vOTU. Connected vOTUs and microbial genomes have matches between the vOTU protospacer sequences and the corresponding microbial spacer sequences. Unconnected circles represent coexisting microbial genomes whose spacer sequences did not match any protospacer sequences.

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