Individual treatment arms after randomization are shown: arm A (n = 4) received only panobinostat (PBT), arm B (n = 9) received panobinostat (PBT) in combination with pegylated IFN-α2a (PEG-IFN-α2a), and arm C (n = 4) received only pegylated IFN-α2a. Time points of PBMC sample collection for analytical purposes are shown.