Line Plot from Scientific Research

Time course of relative fitness of cells expressing KCNE1 variants compared to cells expressing empty vectors. All values are normalized to the values at day 0. Cells expressing KCNE1-HA-WT or two gain-of-function variants (G25V and G60D) depleted over 20 days but cells expressing two loss-of-function variants (D76N and L51H) persisted in the cell pool. Points and error bars indicate mean and standard error of three replicates

DOI