Fold change compared to DMSO of detection of specific rearrangements by RT-PCR, following treatment in Early S for 2 h with ATMi (10 μM), ATRi (4 μM), or ATMi and ATRi together; n ≥ 4, average mean ± SEM, two-sided Student t -test. * ≥ p -value < 0.05 ** ≥ p -value < 0.01, *** ≥ p -value < 0.001