Illustration from Scientific Research

Cartoon depicting the in vivo recording setup (RT-Biolumicorder) used to measure diurnal bioluminescence rhythms in freely moving mice. The mouse is implanted with a luciferin-charged osmotic minipump and dorsally shaved to ensure the detectability of photons emitted from the liver. It is then placed in the arena of the RT-Biolumicorder that records photons via a photomultiplier tube (PMT), activity via infrared detection, and also offers the possibility to program food availability and illumination.

DOI