Schematic representation of the model deduced from the gene expression data from Fig. 1 C (rhythmic 5' IREs for Ftl1, Fth1 and Alas2) and Fig. 1 F-H (rhythmic 3' IRE for Tfrc). The observed rhythms are consistent with minimal and maximal IRP activity at the light-phase (ZT5) and lightdark transition (ZT12) timepoints, respectively.
