Sensitivity robustness assessment. The heatmap illustrates the SCCs between each generic dataset characteristic and the percentage of significant taxa identified by each tool per dataset. Positive correlations are depicted in red, while negative correlations are shown in blue. Stars indicate a significant correlation ( p -value < 0.05). miMic demonstrates robustness across all tested generic features in 16S datasets. For parallel analyses conducted on 16S and WGS cohorts, detailing the percentage of significant taxa identified by each tool per dataset and RSP score, refer to Supplementary Material Fig. S 5