Scatter plot comparing the performance (SP vs. RP) of popular methods across more than 20 different microbial datasets. Each shape represents a distinct cohort with colors matching those indicated in the pie chart ( A ). Dark colors indicate methods with FDR corrections, while light colors represent methods without any corrections. The dashed gray line represents the (y = x) line, where the SP rate is similar to the RP rate. Pink and purple colors in the upper left corner represent miMic and miMic-relative, respectively. In many cases (excluding miMic), the RP and SP rates are similar.
