Microscopy from Scientific Research

Top: PARP1 domain-domain interface variants. II indicates interface between domains. Bottom left: representative fluorescence images of WT and variant PARP1-mEGFP (2 uM) in the presence of Cy3 labeled 45 bp dsDNA (1 uM). Incubation for 30 min at 25°C. Bottom right: the fraction of condensed of WT and variant PARP1. Data obtained from three independent experiments (whiskers: 10th–90th percentiles, horizontal line represents mean value).

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