Scatter Plot from Scientific Research

2D multiparameter fluorescence detection (MFD) histograms for PARP1-DNA complex stoichiometries with contributions from 21 bp dsDNA (Alexa 488) and 21 bp dsDNA (Alexa 647) with unlabeled PARP1 at 10 mM KCl. Orange histogram: simulation for (1:1)n- species (PARP1 with two dsDNA with complex order n) exhibits a narrower stoichiometry distribution than experimental data (black), indicating higher-order (PARP1:DNA)ncomplexes. Dashed orange line: one-to-one donor-to-acceptor ratio.

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