Facial shape effects associated with genetic variants at loci encoding Coordinator-binding TFs (ALX4). LocusZoom plots (left) show SNPs plotted by p value of facial shape association and colored by linkage disequilibrium (r2) to the lead SNP in each locus. Note that p values are with respect to the trait of each lead SNP. Coordinates in hg19. Facial shape effect plots (right) show the normal displacement (displacement in the direction normal to the facial surface) for the facial region (Figure S7A) with the highest significance for each lead SNP.
