Effects of IFN-alpha2a pre-treated neutrophils on the frequencies of Th1/Th17 cells and Tregs in CD4 + T cells from active BU patients (female: n = 4 ; male n = 3 ) and healthy individuals (female: n = 5 ; male: n = 4 ). Data are shown as means +/- SEM. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001. P-values were calculated by the Wilcoxon matched pairs test. In all instances, n refers to the number of each group.