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Depdc5 ncl and Depdc5 tko mice were injected subcutaneously with 5 x 10 5 MC38 tumor cells at day 0. Both Depdc5 ncl and Depdc5 tko mice were divided into two groups: the first group received I.P. injection with 200 g/kg/day DFO, while the second group received I.P. injection vehicle only, beginning day 1 after tumor inoculation. Tumor volumes were then measured at the indicated time points (n = 5).
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