Microscopy from Scientific Research

Examples of annotated tomogram slices from control and A42 oligomer treated neurons. Correlative LysoTracker fluorescence from cryo-SIM data is shown in red. Top left panel (i) in each example is the cryo-SXT image. Top right (ii) shows the correlated cryo-SIM LysoTracker fluorescence data. Bottom left (iii) is the lysosomes annotated onto the cryo-SXT image. Bottom right (iv) is the refined model used for quantitative analysis. Scale bar, 2 m.

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