WT and Slc4a4-icKO mice were intraperitoneally injected with a pan-NOS inhibitor (L-NMMA, 10 mg/kg) from 1 to 3 dpi. Brains were harvested at 4 dpi for analysis of cortical arginine metabolites. Each dot represents an individual animal. n= 47 animals per group.*p< 0.05,**p< 0.01,***p< 0.001 by one-way ANOVA.
