Microscopy from Scientific Research

Representative IF images in CPI-colitis (left) and UC (middle) in colonic tissue sections showing the distribution of CD163 expressing cells (green) in relation to epithelial crypts. FABP1 (red) is used as a crypt top/gradient marker. Scale bar, 100 m. Bar plot (right) showing the number of CD163+peri-cryptal spots, corrected for total peri-cryptal area, in CPI-colitis, UC, and HC tissue sections. Unpaired t test with Welch’s correction, mean values are shown, error bars represent SEM.pvalue < 0.05 ;pvalue < 0.01; ns = not significant.n= 411 samples per condition.

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