Sequence alignment of the G-patch domains of SUGP1, GPATCH8, and GPATCH11. Invariable residues and positions with 70% similarity are highlighted in dark and light pink, respectively. The consensus sequence is shown in red below the alignment with small letters denoting the following: a, aromatic; h, hydrophobic; l, aliphatic; s, small; and u, tiny amino acids. Red arrows indicate the glycine residues mutated in the indicated cDNAs in (B).