Illustration from Scientific Research

Domain structure of HBP1 indicating activation and repression domains and the high-mobility-group (HMG) box (top). HBP1 extreme C-terminal amino acid sequence (aa 502–514) with potential basic motif degron sequence (bold and underlined) aligning with NMNAT1 and YPEL5 binding motifs revealing a consensus sequence (φ represents amino acids with a bulky hydrophobic residue including W, Y, and F).

DOI