Affinities of the germline vs. mature forms of 09-1B12 for group 2 HA trimers (H3 from A/Perth/16/2009 and H7 from A/Shanghai/02/2013) (global fitting from four dilution curves for each antibody type [0.625, 1.25, 2.5, and 5 μM], one experiment). The HC and LC nucleotide sequences of 09-1B12-UCA were derived previously.37Natural gHgL affinities for H7 and H3 trimers are also seen for multiple VH1-18 QxxV bnAb class members (10-610-8M) (Table S3). See alsoFigure S1andTables S1andS2(in relation to B and C).