Imaging (left) and quantification (right) of ICAM-1 expression on CD31+endothelial cells in B16-F10-OVA tumors, harvested at ZT1 or ZT13 from control (pooled of B6 mice andBmal1floxmice), NSG orBmal1ECmice; n= 50, 12, 47, 15, 8, 9, 18, 19 sections, from 16, 4, 15, 5, 3, 3, 5, 5 mice, respectively, from 4 independent experiments, unpaired Student’s t test and cosinor analysis, scale bars: 200 m.
