Numbers of tumor-infiltrating leukocytes in a B16-F10-OVA tumor, harvested as the indicated time points (1 or 13 h in E) after the onset of the cycle under light:dark (LD, n= 3 mice), inverted dark:light (DL, n= 4 mice), or corresponding jet lag (JL, n= 7 mice) conditions, from 3 independent experiments, unpaired Student’s t test. Shaded areas indicate dark phases. All data are represented as mean ± SEM, ns, not significant, ∗p< 0.05;∗∗p< 0.01;∗∗∗p< 0.001. See also Figure S1.
