Summary heatmap of state-state associations across scales in structured samples covering most consensus interactions and other pairs of interest (see alsoData S1). Each column represents the summary of a different spatial relationship measure (Visium data) across all GBM samples, with the final two columns corresponding to CODEX colocalization and regional composition, respectively. Dots are colored by mean scaled relationship strength (coupling score) (STAR Methods), and dot size corresponds to the fraction of samples in which the relationship is significant by Fisher’s exact test.