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Overall statistical consistency between data and model, measured by harmonic mean of four p values from (C) (whole embryo), (D)–(F), as a function of the 2-cell clonal fate bias to become ICM. At ~80:20 bias, P° = 0.05 threshold is crossed. A 70:30 bias was chosen to represent the biased case (yellow) in (B)–(F), (H), and (I), as it is statistically representative without being a statistical edge case.
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