Observed (blue) and statistically predicted (unbiased, red; biased, yellow) distributions of GFP+ cells in 22 blastocysts. Predictions in (B), (F), (H), and (I) are mean ±SD from 104 statistically independent realizations of 22 blastocysts. Random parrest as in Figure S6B (6.5%) and random pdeath in ICM 4.4% from the 64-cell stage. p values in (B) (evaluated directly from the data) are p> 0.05 (ns) or p< 0.05 (*).
