Protein Structure from Scientific Research

The performance of DiG on generating multiple conformations of proteins. Structures generated by DiG (thin ribbons) are compared with the experimentally determined structures (each structure is labelled by its PDB ID, except DEER-AF, which is an AlphaFold predicted model, shown as cylindrical cartoons). For the four proteins (adenylate kinase, LmrP membrane protein, human BRAF kinase and D-ribose binding protein), structures in two functional states (distinguished by cyan and brown) are well reproduced by DiG (ribbons).

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