Serum levels of ALT and AST enzyme levels in four groups of mice. Data are obtained for n = 8 independent biological replicates, mean ± s.e.m. P values in d , f , g , h , j were tested by one-way analysis of variance followed by Tukey–Kramer test. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.