Scatter Plot from Scientific Research

The 15 model-designed peptides were synthesized and their experimental activity against hGCGR measured in triplicate. Here we show the correlation of our predictions ( x axis) with the experimental results ( y axis). The identity line (red dashes) illustrates the ideal case where the predicted value exactly matches the experimental measurement. Data points are coloured by the peptide intended activity: yellow, high potency at GCGR and GLP-1R; blue, GLP-1R-selective; green, GCGR-selective. Error bars denote one standard deviation from the mean, computed over three experimental trials ( n = 3 independent experiments), or the standard deviation from the mean ensemble prediction ( n = 12 predictions made independently by the neural-network model replicas).

DOI