Microscopy from Scientific Research

Snapshots of a rotating doublet labelled with MRLC-iRFP (grey), before and after optogenetic activation of RhoA (dashed red rectangle) generating a local myosin cluster (top: experiments; bottom: simulation; activation at time 0) (see also Supplementary Video 15 and 16 ). In the schematic shown on the left, local Rho activation is indicated by the purple lightning symbol, myosin clusters with a purple dot, cells are outlined by black lines, cellcell junctions are indicated by a green line and the motion of the centre of mass of the doublet by a black arrow. Representative example of n = 9 doublets.

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