Effect of the index variant (rs34951355) associated with differential DT response in African infants on normalized HLA-DRB1 expression in immortalized LCLs from individuals from four African populations (99 individuals from ESN, 112 from GWD, 97 from LWK and 166 from MKK). Only those with more than a single observation in each genotype category are shown. A plot of the data from the pooled set of four populations is also shown. The x -axes numbers refer to the number of copies of the C allele compared to the A allele in each group of individuals per population. Differences between allele copies within the final pooled set were calculated using unadjusted linear regression, P = 4.7 x 10 - 5.
