A Manhattan plot of the genome-wide association analysis of G6. The x axis shows SNP chromosome positions, and the y axis shows the corresponding -log 10 two-tailed P values from the two-sided BOLT infinitesimal model. The horizontal red line indicates the genome-wide significance threshold at P = 5 x 10 -8. The horizontal blue line indicates the suggestive genome-wide significance threshold at P = 1 x 10 -6. The nearest gene or top SNP is highlighted for loci associated at P < 1 x 10 -6.