The Up-LIFT trial was a prospective, single-arm, multicenter, non-significant risk trial designed to evaluate the safety and efficacy of ARC EX Therapy to improve arm and hand functions in people with chronic cervical SCI. Participants were screened and enrolled after a baseline assessment. They then underwent a period of rehabilitation alone followed by ARC EX Therapy for the same period of time. Participants were considered to have completed the trial after finishing all sessions of rehabilitation alone, ARC EX Therapy and all study assessments.