Data are estimated mean (CI) changes from the estimated baseline value in eGFR ( a ) and UACR ( b ), analyzed using an MMRM. The change in UACR was analyzed as the estimated mean ratio to baseline; for ease of interpretation; these ratios were converted to relative percentage changes from baseline using the formula (estimated ratio - 1) x 100. Numbers below the graphs are the number of patients contributing to the analysis. a Given gradual entry to the trial across the enrolment period and variable follow-up duration, data at 156 weeks and 208 weeks are sparser compared to previous timepoints.
