Relative abundance of the indicated histone modification at Hbb-y assayed by either CUT&RUNqPCR or by chromatin immunoprecipitation followed by qPCR (ChIPqPCR) (H3K36me3, H3K79me2), following epigenetic editing or control GFP scFV recruitment in ESCs for 7 d. Shown is the mean of three biologically independent experiments; error bars indicate s.d. Norm., normalized.