Heatmap from Scientific Research

Hi-C contact plot from the K562 cells 57 originally used to design the CRISPRi sgRNA library, with TADs annotated by alternating black and gray bars at the bottom of the figure. The visualized region spans approximately chr2:201,000,000–205,500,000, with the TAD harboring the 2q33.2 costimulatory locus outlined in solid black and expanded in c , d . The dashed line indicates a subdomain harboring the three target genes of interest.

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