Percentages of total reads containing the precise +6 G > T edit (blue) or errors (orange) in Hoxd13 from ear clips of 34 pups developed from embryos microinjected with PE4 components (PE2 editor mRNA, pegRNA and mMLH1dn mRNA) at the two-cell stage. Plot on the right depicts the same data as shown on the left, but with mice sorted into three groups based on the severity of the brachydactyly phenotype of the fifth digit on the front limbs (none, moderate or severe). Boxes indicate the median and IQR of each group with whiskers extending 1.5 x IQR past the upper and lower quartiles.
