Enrichment of MSigDB hallmarks gene sets for tumors using the rank-sorted gene list based on correlation coefficient, quantified by directional log 10 ( Q ): here >0 denotes upregulation in cells with high heteroplasmy truncating variants and <0 denotes downregulation. CI, mitochondrial complex I; CIII, mitochondrial complex III; CIV, mitochondrial complex IV; CV, mitochondrial complex V; rRNA: ribosomal RNA; tRNA, transfer RNA; OLR, light strand origin of replication.
