Percentages of total reads containing the precise +5 G > A edit (blue) or errors (orange) in Chd2 from ear clips of 2- to 3-week-old mice developed from embryos microinjected with PE4 components (PE2 editor mRNA, pegRNA, mMLH1dn mRNA) at the two-cell stage. Data compiled from multiple experiments (Supplementary Table 13 and Methods).